Cell-type-specific asynchronous modulation of PKA by dopamine in finding out
Bromberg-Martin, E. S., Matsumoto, M. & & Hikosaka, O. Dopamine in inspirational control: gratifying, aversive, and signaling. Nerve Cell 68, 815– 834 (2010 ).
Kravitz, A. V. & & Kreitzer, A. C. Striatal systems underlying motion, support, and penalty. Physiology (Bethesda) 27, 167– 177 (2012 ).
Vidal-Gadea, A. G. & & Pierce-Shimomura, J. T. Saved function of dopamine in the modulation of habits. Commun. Integr. Biol 5, 440– 447 (2012 ).
Steinberg, E. E. et al. Favorable support moderated by midbrain dopamine nerve cells needs D1 and D2 receptor activation in the nucleus accumbens. PLoS ONE 9, e94771 (2014 ).
Hikida, T., Kimura, K., Wada, N., Funabiki, K. & & Nakanishi, S. Unique functions of synaptic transmission in direct and indirect striatal paths to reward and aversive habits. Nerve Cell 66, 896– 907 (2010 ).
Tsai, H. C. et al. Phasic shooting in dopaminergic nerve cells suffices for behavioral conditioning. Science 324, 1080– 1084 (2009 ).
Steinberg, E. E. et al. A causal link in between forecast mistakes, dopamine nerve cells and knowing. Nat. Neurosci 16, 966– 973 (2013 ).
Saunders, B. T., Richard, J. M., Margolis, E. B. & & Janak, P. H. Dopamine nerve cells develop Pavlovian conditioned stimuli with circuit-defined inspirational homes. Nat. Neurosci 21, 1072– 1083 (2018 ).
Coddington, L. T. & & Dudman, J. T. The timing of action figures out benefit forecast signals in determined midbrain dopamine nerve cells. Nat. Neurosci 21, 1563– 1573 (2018 ).
Schultz, W., Dayan, P. & & Montague, P. R. A neural substrate of forecast and benefit. Science 275, 1593– 1599 (1997 ).
Cohen, J. Y., Haesler, S., Vong, L., Lowell, B. B. & & Uchida, N. Neuron-type-specific signals for benefit and penalty in the forward tegmental location. Nature 482, 85– 88 (2012 ).
Eshel, N., Tian, J., Bukwich, M. & & Uchida, N. Dopamine nerve cells share typical action function for benefit forecast mistake. Nat. Neurosci 19, 479– 486 (2016 ).
Day, J. J., Roitman, M. F., Wightman, R. M. & & Carelli, R. M. Associative finding out moderates vibrant shifts in dopamine signaling in the nucleus accumbens. Nat. Neurosci 10, 1020– 1028 (2007 ).
Shen, W., Flajolet, M., Greengard, P. & & Surmeier, D. J. Dichotomous dopaminergic control of striatal synaptic plasticity. Science 321, 848– 851 (2008 ).
Gerfen, C. R. et al. D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal nerve cells. Science 250, 1429– 1432 (1990 ).
Kupchik, Y. M. et al. Coding the direct/indirect paths by D1 and D2 receptors is not legitimate for accumbens forecasts. Nat. Neurosci 18, 1230– 1232 (2015 ).
Skeberdis, V. A. et al. Protein kinase A controls calcium permeability of NMDA receptors. Nat. Neurosci 9, 501– 510 (2006 ).
Lee, H. K. et al. Phosphorylation of the AMPA receptor GluR1 subunit is needed for synaptic plasticity and retention of spatial memory. Cell 112, 631– 643 (2003 ).
Yagishita, S. et al. An important time window for dopamine actions on the structural plasticity of dendritic spinal columns. Science 345, 1616– 1620 (2014 ).
Iino, Y. et al. Dopamine D2 receptors in discrimination knowing and spinal column augmentation. Nature 579, 555– 560 (2020 ).
Lau, G. C., Saha, S., Faris, R. & & Russek, S. J. Up-regulation of NMDAR1 subunit gene expression in cortical nerve cells through a PKA-dependent path. J. Neurochem 88, 564– 575 (2004 ).
Nayak, A., Zastrow, D. J., Lickteig, R., Zahniser, N. R. & & Browning, M. D. Upkeep of late-phase LTP is accompanied by PKA-dependent boost in AMPA receptor synthesis. Nature 394, 680– 683 (1998 ).
Lee, S. J., Chen, Y., Lodder, B. & & Sabatini, B. L. Keeping an eye on behaviorally caused biochemical modifications utilizing fluorescence life time photometry. Front. Neurosci 13, 766 (2019 ).
Chen, Y., Saulnier, J. L., Yellen, G. & & Sabatini, B. L. A PKA activity sensing unit for quantitative analysis of endogenous GPCR signaling through 2-photon FRET-FLIM imaging. Front. Pharmacol 5, 56 (2014 ).
Chen, Y. et al. Endogenous Gαq-coupled neuromodulator receptors trigger protein kinase A. Nerve Cell 96, 1070– 1083. e5 (2017 ).
Mohebi, A. et al. Dissociable dopamine characteristics for finding out and inspiration. Nature 570, 65– 70 (2019 ).
Dana, H. et al. Delicate red protein calcium indications for imaging neural activity. eLife 5, e12727 (2016 ).
Patriarchi, T. et al. Ultrafast neuronal imaging of dopamine characteristics with developed genetically encoded sensing units. Science 360, eaat4422 (2018 ).
Klapoetke, N. C. et al. Independent optical excitation of unique neural populations. Nat. Techniques 11, 338– 346 (2014 ).
Mahn, M. et al. High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins. Nat. Commun 9, 4125 (2018 ).
Howe, M. W., Tierney, P. L., Sandberg, S. G., Phillips, P. E. M. & & Graybiel, A. M. Extended dopamine signalling in striatum signals distance and worth of far-off benefits. Nature 500, 575– 579 (2013 ).
Matamales, M. et al. Regional D2- to D1-neuron transmodulation updates goal-directed knowing in the striatum. Science 367, 549– 555 (2020 ).
Jiang, S. Z. et al. NCS-Rapgef2, the protein item of the neuronal Rapgef2 gene, is a particular activator of D1 dopamine receptor-dependent ERK phosphorylation in mouse brain. eNeuro 4, ENEURO.0248-17.2017 (2017 ).
Ilango, A. et al. Comparable functions of substantia nigra and forward tegmental dopamine nerve cells in benefit and hostility. J. Neurosci 34, 817– 822 (2014 ).
Goto, A. et al. Circuit-dependent striatal PKA and ERK signaling underlies fast behavioral shift in breeding response of male mice. Proc. Natl Acad. Sci. U.S.A. 112, 6718– 6723 (2015 ).
Yamaguchi, T. et al. Function of PKA signaling in D2 receptor-expressing nerve cells in the core of the nucleus accumbens in aversive knowing. Proc. Natl Acad. Sci. U.S.A. 112, 11383– 11388 (2015 ).
Ma, L. et al. An extremely delicate A-kinase activity press reporter for imaging neuromodulatory occasions in awake mice. Nerve Cell 99, 665– 679. e5 (2018 ).
Collins, A. G. E. & & Frank, M. J. Challenger star knowing (OpAL): modeling interactive impacts of striatal dopamine on support knowing and option reward. Psychol. Rev 121, 337– 366 (2014 ).
Gurney, K. N., Humphries, M. D. & & Redgrave, P. A brand-new structure for cortico-striatal plasticity: behavioural theory fulfills in vitro information at the reinforcement-action user interface. PLoS Biol 13, e1002034 (2015 ).
Gerfen, C. R. & & Surmeier, D. J. Modulation of striatal forecast systems by dopamine. Annu. Rev. Neurosci 34, 441– 466 (2011 ).
Gerfen, C. R., Paletzki, R. & & Heintz, N. GENSAT BAC Cre-recombinase motorist lines to study the practical company of cerebral cortical and basal ganglia circuits. Nerve Cell 80, 1368– 1383 (2013 ).
Bäckman, C. M. et al. Characterization of a mouse pressure revealing Cre recombinase from the 3 ′ untranslated area of the dopamine transporter locus. Genesis 44 , 383– 390 (2006 ).
Lee, S. J., Escobedo-Lozoya, Y., Szatmari, E. M. & & Yasuda, R. Activation of CaMKII in single dendritic spinal columns throughout long-lasting potentiation. Nature 458, 299– 304 (2009 ).
Pnevmatikakis, E. A. et al. Synchronised denoising, deconvolution, and demixing of calcium imaging information. Nerve Cell 89, 285– 299 (2016 ).
Motulsky, H. J. How to report the techniques utilized for the blended design analysis https://www.graphpad.com/guides/prism/8/statistics/stat_how-to-report-the-methods-used.htm (2020 ).
